If you are using Windows Server 2016 with dedup an important KB is to install; KB4025334 !
There is a quote why;
KB4025334 prevents a critical data corruption issue with NTFS sparse files in Windows Server 2016. This helps avoid data corruptions that may occur when using Data Deduplication in Windows Server 2016, although all applications and Windows components that use sparse files on NTFS benefit from applying this update. Installation of this KB helps avoid any new or further corruptions for Data Deduplication users on Windows Server 2016.
Quote from there